Adding a missing protein to infertile human sperm can increase its ability to fertilize an egg, dramatically raising the odds of a successful pregnancy.
“We know that some men are infertile because their sperm fail to activate eggs. Even though their sperm fuses with the egg, nothing happens. These sperm may lack a proper functioning version of PLCz, which is essential to trigger the next stage in becoming pregnant,” says Tony Lai, professor at Cardiff University.
“What’s important from our research is that we have used human sperm PLCz to obtain the positive results that we had previously observed only in experiments with mice.”
Full story at Futurity.
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