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The National Academy of Sciences did a thorough review on fluoride in 2006. They documented numerous deleterious effects of fluoride on many organ systems including increased potential risk for bone fractures (the well characterized disease of skeletal fluorosis) possibly increased risk of osteosarcoma, reduced IQ, thyroid dysfunction, endocrine dysfunction and others all 300 pages is online if anyone cares to confirm it. Of course don't forget fluoride induced dental fluorsosis (i.e. teeth mottling and a sign of toxic exposure to fluoride) They ended with recommending that the EPA should more strictly regulate fluoride. Their findings mirror those in the peer-reviewed medical literature, while Harvard trained toxicologist also extensively documented behavioral changes in mice upon exposure to blood levels of fluoride not far greater than those experienced through water fluoridation and other sources of exposure. Former, well credentialed EPA scientists have been fired for bucking the political line on this issue. Meanwhile 90% of the fluoride placed into our water supply is not industrial grade sodium fluoride, it is silicofluorides, quite simply, scraped from the sides of Florida phosphate plant smokestacks. If it weren't thrown into the water supply it would have to be disposed of as hazardous waste. You can read more on this starting here http://healthjournalclub.blogspot.com/2009/11/water-fluoridation-part-i.html if you suspect I am just making this all up. What a great government we have.