Scientists have combined MRI and imaging mass spectrometry to visualize the body’s inflammatory response to a bacterial infection in 3D.
“Imaging mass spectrometry is extremely valuable for the discovery process because it does not require a target-specific reagent such as an antibody—that is, you do not have to know in advance what you’re looking for in order to correlate molecular changes with disease outcome,” says senior author Richard Caprioli of Vanderbilt University.
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Photo credit: Vanderbilt